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como el Magnesio Liposomal puede transformer tus formulaciones

How Liposomal Magnesium Can Enhance Your Formulations

Discover the magnesium that reaches where others do not and can transform your formulations and consumer health.

Liposovit-Mg: High-Performance Liposomal Magnesium for Advanced Nutraceutical Formulations

If you’re a formulator searching for the most advanced ingredients, we present Liposovit-Mg. This liposomal magnesium powder sets a new standard in bioavailability and efficacy. Designed to meet the highest technical and quality demands, Liposovit-Mg is ready to redefine your formulations.

Liposomal Technology: A Decisive Advantage in Magnesium

Liposovit-Mg se distingue por su innovadora tecnología liposomal, una solución avanzada que supera las limitaciones de las formas convencionales de magnesio.

Absorption of Liposovit-Mg stands out with its innovative liposomal technology, an advanced solution that surpasses the limitations of conventional magnesium forms.

This technology is based on:

  • Precise Encapsulation: Magnesium citrate is encapsulated in nanometric-sized lipid vesicles, composed of phospholipids that mimic the structure of cell membranes. This encapsulation facilitates its absorption in the small intestine.
  • Optimized Bioavailability: The liposomes transport the magnesium through the intestinal wall, where they release it directly into the bloodstream. This maximizes the magnesium’s bioavailability and efficacy in the body.
  • Targeted Delivery: Liposomal encapsulation also allows for more controlled release of the magnesium, optimizing its utilization and reducing the risk of side effects.

Additionally, the liposome dehydration applied:

  • Significantly increases the storage stability of the final product compared to its liquid form
  • Eliminates the need to maintain refrigerated temperatures during transport, distribution and storage of the formulation.
  • Eliminates the need to add preservatives
  • Increases the range of possible applications of the product, adapting it for easy encapsulation and convenient use in powder mixtures.

Human Study: Strong Evidence of Liposovit-Mg Superiority

The efficacy of Liposovit-Mg is not just a claim, but the result of an in vivo human intervention.The comparative crossover pilot study evaluated the bioavailability of Liposovit-Mg against a conventional form of magnesium (magnesium citrate), yielding the following results:

Greater bioavailability expressed as the Area Under the Curve (AUC): Liposovit-Mg demonstrated a significantly higher AUC compared to magnesium citrate (87.6 ± 15.9 mEq x h/L vs. 84.7 ± 15.6 mEq x h/L, p<0.05), confirming its greater bioavailability.

Maximum Concentration (Cmax): Liposovit-Mg achieved a slightly higher maximum serum concentration than magnesium citrate (1.9 ± 0.1 mEq/L vs. 1.8 ± 0.05 mEq/L). Although the difference was not statistically significant, the trend favored the liposomal form.

Time to Maximum Concentration (Tmax): The time required to reach maximum concentration was higher for Liposovit-Mg as compared to its conventional counterpart (10.3 ± 7.4 h vs. 7.3 ± 4.5 h), although the difference was not statistically significant.

Concentration at 48h (C48h): Serum magnesium levels at 48 hours post-administration remained statistically higher than baseline levels for Liposovit-Mg (p=0.011), whereas magnesium citrate concentrations decreased to pre-dose levels at 48h. This indicates more prolonged duration of elevated blood concentrations of liposomal magnesium.

Characteristics of Liposovit-Mg

  • Forma: Polvo fino y homogéneo, de color beige claro a oscuro.
  • Composición: Liposomas con magnesio citrato encapsulado, sin OMG, alcohol, conservantes ni alérgenos.
  • Tamaño de Partícula:
    • Tamaño promedio de 320 nm (D50).
    • Media armónica: 316.4 nm.
    • Desviación estándar: 81.37 nm.
    • Moda: 266.3 nm.
  • Integridad de las micropartículas de polvo confirmada mediante el uso de Microscopía Electrónica de Barrido (SEM)
Partículas de polvo Liposovit®-Mg en imágenes obtenidas al microscopio electrónico de barrido
Liposovit®-Mg powder particles in scanning electron microscope images

Liposome integrity and homogeneity confirmed by cryo-transmission electron microscopy (cryo-TEM)

Morfología de los liposomas en Liposovit®-Mg, en imágenes del microscopio electrónico criogénico (Tecnai F20 X TWIN, FEI Company)
A. vesícula multivesicular (MVV), B. vesícula oligolamelar (OLV).
Morphology of liposomes in Liposovit®-Mg, in cryogenic electron microscope images (Tecnai F20 X TWIN, FEI Company) A. multivesicular vesicle (MVV), B. oligolamellar vesicle (OLV).

Average liposome particle size: 320 nm
Stability: 24 months under specific storage conditions (5-25 °C, humidity 25-70%.

Liposovit-Mg DIRECT: Optimization of Granule Formulation

For formulations that require even greater practicality and performance, Bart offers Liposovit-Mg DIRECT, a granulated presentation that stands out for:

  • Fastener Dissolution Rate: Facilitates faster dissolution in water.
  • Better Flow: Simplifies handling and incorporation into powder mixtures.
  • Less Dust: Reduces dust generation during handling, improving cleanliness in the production environment.
  • Less Hygroscopicity: Less tendency to absorb moisture from the environment, which increases product stability.
  • Convenient Dosing: Allows precise and comfortable dosing.

Key Applications for Formulators

Liposovit-Mg is ideal for a wide range of applications, including:

  • Different formats of food supplements: capsules, tablets or sachets
  • Fortified foods
  • Powder mixes containing other nutrients, such as vitamins, minerals and plant extracts, including other Liposovit® products.

Bart’s Commitment to Quality and Innovation

Liposovit-Mg is the result of Bart’s commitment to quality, innovation and scientific research. They are dedicated to providing formulators with tools and solutions that enable them to create cutting-edge products that make a difference in the health and well-being of their consumers.l bienestar de sus consumidores.

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BART: Leader in Liposomal Technology

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