Discover the magnesium that reaches where others cannot and can transform your formulations and consumer health.

Liposovit-Mg: High-Performance Liposomal Magnesium for Advanced Nutraceutical Formulations

If you’re a formulator searching for the most advanced ingredients, we present Liposovit-Mg. This liposomal magnesium powder sets a new standard in bioavailability and efficacy. Designed to meet the highest technical and quality demands, Liposovit-Mg is ready to redefine your formulations.

Liposomal Technology: A Decisive Advantage in MagnesiumAbsorption of Liposovit-Mg stands out with its innovative liposomal technology, an advanced solution that surpasses the limitations of conventional magnesium forms.

This technology is based on:

• Precise Encapsulation: Magnesium citrate is encapsulated in nanometric-sized lipid vesicles, composed of phospholipids that mimic the structure of cell membranes. This encapsulation facilitates its absorption in the small intestine.
• Optimized Bioavailability: The liposomes transport the magnesium through the intestinal wall, where they release it directly into the bloodstream. This maximizes the magnesium’s bioavailability and efficacy in the body.
• Targeted Delivery: Liposomal encapsulation also allows for more controlled release of the magnesium, optimizing its utilization and reducing the risk of side effects.

Additionally,  the liposome dehydration applied:

• Increases the range of possible applications of the product, adapting it for easy encapsulation and convenient use in powder mixtures.
• Significantly increases the storage stability of the final product compared to its liquid form
• Eliminates the need to maintain refrigerated temperatures during transport, distribution, and storage of the formulation
• Eliminates the need to add preservatives

Human Study: Strong Evidence of Liposovit-Mg Superiority

The efficacy of Liposovit-Mg is not just a claim, but the result of an in vivo human intervention. The comparative crossover pilot study evaluated the bioavailability of Liposovit-Mg against a conventional form of magnesium (magnesium citrate), yielding the following results:

• Greater bioavailability expressed as the Area Under the Curve (AUC): Liposovit-Mg demonstrated a significantly higher AUC compared to magnesium citrate (87.6 ± 15.9 mEq x h/L vs. 84.7 ± 15.6 mEq x h/L, p<0.05), confirming its greater bioavailability.
• Maximum Concentration (Cmax): Liposovit-Mg achieved a slightly higher maximum serum concentration than magnesium citrate (1.9 ± 0.1 mEq/L vs. 1.8 ± 0.05 mEq/L). Although the difference was not statistically significant, the trend favored the liposomal form.
• Time to Maximum Concentration (Tmax): The time required to reach maximum concentration was higher for Liposovit-Mg as compared to its conventional counterpart (10.3 ± 7.4 h vs. 7.3 ± 4.5 h), although the difference was not statistically significant.
• Concentration at 48h (C48h): Serum magnesium levels at 48 hours post-administration remained statistically higher than baseline levels for Liposovit-Mg (p=0.011), whereas magnesium citrate concentrations decreased to pre-dose levels at 48h. This indicates more prolonged duration of elevated blood concentrations of liposomal magnesium.

Characteristics of Liposovit-Mg

• Form: Fine and homogeneous powder, from light beige to dark beige.
• Composition: Liposomes with encapsulated magnesium citrate, free of GMOs, alcohol, preservatives, and allergens.
• Integrity of the powder microparticles confirmed with the use of Scanning Electron Microscopy (SEM)

Integrity and homogeneity of the liposomes confirmed under Cryo-Transmission Electron Microscopy (cryo-TEM)

Average liposome particle size: 320 nm Stability: 24 months under specified storage conditions (5-25°C, humidity 25-70%).

Liposovit-Mg DIRECT: Optimization of Granule Formulation

For formulations that require even greater practicality and performance, Bart offers Liposovit-Mg DIRECT, a granulated presentation that stands out for:

Faster Dissolution Rate: Facilitates quicker dissolution in water.

Better Flow: Simplifies handling and incorporation into powder blends.

Reduced Dust: Minimizes dust generation during handling, improving cleanliness in the production environment.

Lower Hygroscopicity: Less tendency to absorb ambient moisture, which increases product stability.

Convenient Dosage: Allows for precise and convenient dosages

Key Applications for Formulators

Liposovit-Mg is ideal for a wide range of applications, including:

• Different formats of dietary supplements: capsules, tablets or sachets
• Fortified foods
• Powder mixtures containing other nutrients, such as vitamins, minerals, and plant extracts, including other Liposovit® products

Bart’s Commitment to Quality and Innovation

Liposovit-Mg is the result of Bart’s commitment to quality, innovation, and scientific research. They are dedicated to providing formulators with the tools and solutions to create cutting-edge products that make a difference in consumer health and well-being.

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